Publikationen 2013

publications 2013

Bonn M, Schmitt A, Lesch KP, Van Bockstaele EJ, Asan E (2012) Serotonergic innervation and serotonin receptor expression of NPY-producing neurons in the rat lateral and basolateral amygdaloid nuclei. Brain Struct Funct 18:421-35

Heinzel S, Dresler T, Baehne CG, Heine M, Boreatti-Hümmer A, Jacob CP, Renner TJ, Reif A, Lesch KP, Fallgatter AJ, Ehlis AC (2012) COMT x DRD4 epistasis impacts prefrontal cortex function underlying response control. Cereb Cortex May 22 [Epub ahead of print]

Waider J, Proft F, Langlhofer G, Asan E, Lesch KP, Gutknecht L (2012) GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice. Histochem Cell Biol 24:1225-1235

Weissflog L, Scholz CJ, Jacob CP, Nguyen TT, Zamzow K, Groß-Lesch S, Renner TJ, Romanos M, Rujescu D, Walitza S, Kneitz S, Lesch KP, Reif A (2013) KCNIP4 as a candidate gene for personality disorders and adult ADHD. Eur Neuropsychopharmacol, Sep 13 [Epub ahead of print]

Hahn T, Marquand AF, Plichta MM, Ehlis AC, Schecklmann MW, Dresler T, Jarczok TA, Eirich E, Leonhard C, Reif A, Lesch KP, Brammer MJ, Mourao-Miranda J, Fallgatter AJ (2012) A novel approach to probabilistic biomarker-based classification using functional near-infrared spectroscopy. Hum Brain Mapp 34:1102-1114

Dentel C, Palamiuc L, Henriques A, Lannes B, Spreux-Varoquaux O, Gutknecht L, Rene F, Echaniz-Laguna A, Gonzalez de Aguilar JL, Lesch KP, Meininger V, Loeffler JP, Dupuis L (2012) Degeneration of serotonin neurons in amyotrophic lateral sclerosis: a link to spasticity. Brain 136:483-493

Van den Hove DLA, Kenis G, Brass A, Rutten BPF, Bruschettini M, Blanco CE, Lesch KP, Steinbusch HWM, Prickaerts J (2012) Vulnerability versus resilience to prenatal stress in male versus female Sprague-Dawley rats; implications from gene expression profiles in the hippocampus and frontal cortex. Eur Neuropsychopharmacol, Nov 27 [Epub ahead of print]

Fallgatter AJ, Ehlis AC, Dresler T, Reif A, Jacob C, Arcos-Burgos M, Muenke M, Lesch KP (2012) Influence of a Latrophilin 3 (LPHN3) risk haplotype on event-related potential measures of cognitive response control in attention-deficit/hyperactivity disorder (ADHD). Eur Neuropsychopharmacology, Dec 11 [Epub ahead of print]

Enge S, Fleischhauer M, Lesch KP, Reif A, Strobel A (2012) Variation in key genes of serotonin and norepinephrine function predicts gamma-band activity during goal-directed attention. Cereb Cortex, Dec 20 [Epub ahead of print]

Heiming RS, Mönning A, Jansen F, Kloke V, Lesch KP, Sachser N (2013) To attack, or not to attack? The role of serotonin transporter genotype in the display of maternal aggression. Behav Brain Res 242:135-141

Laas K, Reif A, Kiive E, Domschke K, Lesch KP, Veidebaum T, Harro J.A functional NPSR1 gene variant and environment shape personality and impulsive action: A longitudinal study. J Psychopharmacol. 2013 Jan 16. [Epub ahead of print]

Schartl M, Walter RB, Shen Y, Garcian T, Catchen J, Amores A, Braasch I, Chalopin D, Volff JN, Lesch KP, Bisazza A, Minx P, Wilson RK, Fuerstenberg S, Boore J, Postlethwait JH, Warren WC (2013) The genome of the platyfish, Xiphophorus maculatus: insights into complex traits. Nat Genetics 45:567-572

Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, Kendler K, Lee PH, Neale BM, Nurnberger JI, Ripke S, Santangelo S, Sullivan PF, … Lesch KP, …, Craddock N, Kendler K (2013) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381:1371-1379

Hohoff C, Gorji A, Kaiser S, Willscher E, Korsching E, Ambrée O, Arolt V, Lesch KP, Sachser N, Deckert J, Lewejohann L (2013) Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice. PLoS One 8:e58880

Albayrak O, Pütter C, Volckmar AL, Cichon S, Hoffmann P, Nöthen MM, Jöckel KH, Schreiber S, Wichmann HE, Faraone SV, Neale BM, Herpertz-Dahlmann B, Lehmkuhl G, Sinzig J, Renner TJ, Romanos M, Warnke A, Lesch KP, Reif A, Schimmelmann BG, Scherag A, Hebebrand J, Hinney A; Psychiatric GWAS Consortium: ADHD Subgroup (2013) Common obesity risk alleles in
childhood attention-deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet, Mar 26 [Epub ahead of print]

Hamshere ML, Langley K, Martin J, Agha SS, Stergiakouli E, Anney RJ, Buitelaar J, Faraone SV, Lesch KP, Neale BM, Franke B, Sonuga-Barke E, Asherson P, Merwood A, Kuntsi J, Medland SE, Ripke S, Steinhausen HC, Freitag C, Reif A, Renner TJ, Romanos M, Romanos J, Warnke A, Meyer J, Palmason H, Vasquez AA, Lambregts-Rommelse N, Roeyers H, Biederman J, Doyle AE, Hakonarson H, Rothenberger A, Banaschewski T, Oades RD, McGough JJ, Kent L, Williams N, Owen MJ, Holmans P, O'Donovan MC, Thapar A (2013) High Loading of Polygenic Risk for ADHD
in Children With Comorbid Aggression. Am J Psychiatry, Apr 19 [Epub ahead of print]

Kloke V, Heiming RS, Bölting S, Kaiser S, Lewejohann L, Lesch KP, Sachser N (2013) Unexpected effects of early-life adversity and social enrichment on the anxiety profile of mice varying in serotonin transporter genotype. Behav Brain Res 247C:248-258

Asan E, Steinke M, Lesch KP (2013) Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety. Histochem Cell Biol, Mar 15 [Epub ahead of print]

Araragi N, Lesch KP (2013) Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and tryptophan hydroxylase-2 knockout mouse models. Curr Drug Targets 14:549-570