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Publikationen 2006

Publications 2006


  1. Leonhard C, Beck M, Reif A, Jacob CP, Lesch KP (2006) Transient ischemic attack associated with short-term methylphenidate medication. Int J Neuropsychopharmacology 9:129-130
  2. Sanjuan J, Rivero O, Aguilar EJ, González JC, Molto MD, de Frutos R, Lesch KP, Najera C (2006) Serotonin transporter gene polymorphism (5-HTTLPR) and emotional response to auditory hallucinations in schizophrenia. Int J Neuropsychopharmacol 9:131-133
  3. Wendland JR, Hampe M, Newman TK, Syagailo Y, Meyer J, Schempp W, Timme A, Suomi SJ, Lesch KP (2006) Structural variation of ther monoamine oxidase A gene promoter repeat polymorphism in nonhuman primates. Genes Brain Behav 5:40-45
  4. Reif A, Strobel A, Jacob CP, Herterich S, Freitag CM, Töpner T, Mössner R, Fritzen S, Schmitt A, Lesch KP (2006) A NOS-III haplotype that includes functional polymorphisms is associated with bipolar disorder. Int J Neuropsychopharmacol 9: 13-20
  5. Wendland JR, Martin B, Kruse MR, Lesch KP, Murphy DL (2006) Simultaneous genotyping of four functional loci of human SLC6A4, with a note on 5-HTTLPR and rs25531. Mol Psychiatry 11:224-226
  6. Reif A, Fritzen S, Finger M, Lauer M, Schmitt A, Lesch KP (2006) Adult neurogenesis in th human hippocampus is altered in schizophrenia but not depression. Mol Psychiatry Jan 11:514-522
  7. Mössner R, Freitag CM, Gutknecht L, Reif A, Tauber R, Franke P, Fritze J, Wagner G, Peikert G, Wenda B, Sand P, Rietschel M, Garritsen H, Jacob C, Lesch KP, Deckert J (2006) The novel brain-specific tryptophan hydroxylase-2 gene in panic disorder. J Psychopharmacology 20:547-552
  8. Ren-Patterson RF, Cochran LW, Holmes A, Lesch KP, Lu B, Murphy DL (2006) Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol 26:753-78
  9. Reif A, Herterich S, Strobel A, Ehlis AC, Saur D, Jacob CP, Wienker T, Töpner T, Fritzen S, Walter U, Schmitt A, Fallgatter AJ, Lesch KP (2006) A neuronal nitric oxide synthase (NOS-I)haplotype associated with schizophrenia modifies prefrontal cortex function. Mol Psychiatry 11:286-300
  10. Mössner R, Simantov R, Marx A, Lesch KP, Seif I (2006) Aberrant accumulation of serotonin in dopaminergic neurons. Neurosci Lett. 401:49-54.
  11. Hensch T, Wargelius HL, Herold U, Lesch KP, Oreland L, Brocke B (2006) Further evidence for an association of 5-HTTLPR with intensity dependence of auditory evoked potentials. Neuropsychopharmacology Jan 18 (Epub ahead of print)
  12. Wendland JF, Lesch KP, Newman TK, Timme A, Gachot-Neveu H, Thierry B, Suomi SJ (2006) Differential functional variability of serotonin transporter and monoamine oxidase A genes in macaque species displaying contrasting levels of aggression-related behavior. Behav Genet 36:163-72
  13. Mössner R, Walitza S, Geller F, Scherag A, Gutknecht L, Bogusch L, Remschmidt H, Simons M, Herpertz-Dahlmann B, Fleischhaker C, Schulz E, Warnke A, Hinney A, Wewetzer C, Lesch KP (2005) Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder. Int J Neuropsychopharamcol 9:437-442
  14. Freitag CM, Domschke K, Rothe C, lee YY, Hohoff C, Gutknecht L, Sand P, Fimmers R, Lesch KP, Deckert J (2006) Interaction of serotonergic and noradrenergic gene variants in panic disorder. Psychiatr Genetics 16:59-65
  15. Alexandre C, Popa D, Fabre V, Bouali S, Venault P, Lesch KP, Hamon M, Adrien J (2006) Early-life blockade of 5-HT1A receptors normalizes sleep and depression-like behavior in adult knock-out mice lacking the serotonin transporter. J Neurosci 26:5554-5564
  16. Loucif ALC, Bonnavion P, Macri B, Golmard JL, Boni C, Melfort M, Leonard G, Lesch KP, Arien J, Jacquin TD (2006) Gender-dependent regulation of G-protein-gated inwardly rectifying potassium current in dorsal raphe neurons in knock-out mice devoid of 5-hydroxytrypptamine transporter. J Neurobiol 66:1475-1488
  17. Mössner R, Yun SW, Lesch KP, Gerlach M, Klein MA, Riederer P (2006) Unaltered susceptibility to scrapie in serotonin transporter deficient mice. Neurochem Int May 25 (Epub ahead of print)
  18. Canli T, Qiu M, Omura K, Congdon E, Haas BW, Amin Z, Herrmann MJ, Constable RT, Lesch KP (2006) Neural correlates of epigenesis. Proc Natl Acad Sci USA 103:16033-16038
  19. Brocke B, Armbruster D, Müller J, Hensch T, Jacob C, Lesch KP, Kirschbaum C,, Strobel A (2006) Serotonin transporter gene variation impacts on innate fear processing: acoustic startle response modulated by stimuli of emotional valence. Mol Psychiatry 2006 Oct 10 (Epub ahead of print)
  20. Bringmann G, Feineis D, Munchbach M, God R, Peters K, Peters EM, Mössner R, Lesch KP (2006) Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in PC12 cells. Z Naturforsch [C] 61:601-610
  21. Jacob C, Lesch KP (2006) The Wuerzburg Research Initiative on Adult Attention-Deficit/Hyperactivity Disorder (WURIN-AADHD): multi-layered evaluation of long-term course. Eur Arch Psychiatry Clin Neurosci 256 Suppl 1:12-20
  22. Fallgatter AJ, Lesch KP (2006) 22q11.2 deletion syndrome as a natural model for COMT haploinsufficiency-related dopaminergic dysfunction in ADHD. Int J Neuropsychopharmacol. 2006 Jul 19 (Epub ahead of print)
  23. Lesch KP, Canli T (2006) 5-HT1A receptor and anxiety-related traits: pharmacology, genetics, and imaging. In: Canli T (Ed.) Biology of Personality and Individual Differences. Guilford, New York pp. 273-294
  24. Lesch KP, Mössner R (2006) Inactivation of serotonin (5HT) transport: modeling altered 5HT homeostasis implicated in emotional dysfunction, affective disorders, and somatic syndromes. In: Sitte H. (ed.) Handbook of Experimental Pharmacology. Vol. 175, Anxiety and anxiolytic drugs. Springer, Berlin, Heidelberg, New York pp. 417-456