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Publikationen 2004

Publications 2004


  1. Mössner R, Schmitt A, Hennig T, Bennninghoff J Gerlach M, Riederer P, Deckert J, Lesch KP (2004) Quantitation of 5-HT3 receptors in forebrain of serotonin transporter deficient mice. J Neural Transm 111:27-35
  2. Rothe C, Gutknecht L, Freitag CM, Tauber R, Franke P, Fritze J, Wagner G, Peikert G, Wenda B, Sand P, Jacob C, Rietschel M, Nöthen MM, Garritsen H, Fimmers R, Deckert J, Lesch KP (2004) Association of a functional -1019C>G 5-HT1A receptor gene polymorphism with panic disorder with agoraphobia. Int J Neuropsychopharmacol 7:189-192
  3. Rumajogee P, Verge D, Hanoun N, Brisorgueil MJ, Hen R, Lesch KP, Hamon M, Miquel MC (2004) Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP. Eur J Neurosci 19:937-44
  4. Jacob CP, Strobel A, Hohenberger K, Ringel T, Gutknecht L, Reif A, Brocke B, Lesch KP (2004) Association between allelic variation of serotonin transporter function and Neuroticism in anxious cluster C personality disorders. Am J Psychiatry 161:569–572
  5. Marziniak M, Mossner R, Benninghoff J, Syagailo YV, Lesch KP, Sommer C (2004) Association analysis of the functional monoamine oxidase A gene promotor polymorphism in migraine. J Neural Transm 111:603-609
  6. La Cour CM, Hanoun N, Melfort M, Hen R, Lesch KP, Hamon M, Lanfumey L (2004) GABA receptors in 5-HT transporter- and 5-HT receptor-knockout mice: further evidence of a transduction pathway shared with 5-HT receptors. J Neurochem 89:886-896
  7. Domschke K, Freitag CM, Kuhlenbäumer G, Schirmacher A, Sand P, Nyhuis P, Jacob C, Fritze J Franke P, Rietschel M, Garritsen HS, Nöthen MM, Lesch KP, Stögbauer F, Deckert J (2004) Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women. Int J Neuropsychopharmacol 7:183-188
  8. Reif A, Kress W, Wurm K, Benninghoff J, Pfuhlmann B, Lesch KP (2004) Duplication 15q14®pter: a rare chromosomal abnormality underlying bipolar affective disorder. Eur Psychiatry 19:179-181
  9. Fallgatter AJ, Herrmann MJ, Roemmler J, Ehlis AC, Wagener A, Heidrich A, Zeng Y, Ortega G, Lesch KP (2004) Allelic variation of serotonin transporter function modulates the brain electrical response for error processing. Neuropsychopharmacology 29:1506-1511
  10. Barr CS, Newman TK, Shannon C, Parker C, Dvoskin RL, Becker ML, Schwandt M, Champoux M, Lesch KP, Goldman D, Suomi SJ, Higley JD (2004) Rearing condition and rh5-HTTLPR interact to influence LHPA-axis response to stress in infant macaques. Biol Psychiatry 55:733-738
  11. Barr CS, Newman TK, Lindell S, Shannon C, Champoux M, Lesch KP, Suomi SJ, Goldman D, Higley JD (2004) Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates. Arch Gen Psychiatry 61:1146-1152
  12. Shen HW, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I, (2004) Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology 29:1790-1799
  13. Reif A, Schmitt A, Fritzen S, Bartsch C, Wycislo M, Mössner R, Sommer C, Lesch KP (2004) Differential effect of endothelial nitric oxide synthase (NOS III) on the regulation of adult neurogenesis. Eur J Neurosci 20:885-895
  14. Mössner R, Weichselbaum A, Marziniak M, Freitag C, Lesch KP, Sommer C, Meyer J (2004) A highly polymorphic poly-glutamine stretch in the potassium channel KCNN3 in migraine with and without aura. Headache 45:132-136
  15. Barr CS, Newman TK, Shannon C, Dvoskin RL, Lindell S, Taubman J, Champoux M, Lesch KP*, Goldman D*, Suomi SJ*, Higley JD* (2004) Early adversity and serotonin transporter gene promoter variation interact to influence stress axis response in female, but not male, infant macaques. Proc Natl Acad Sci U S A 101:12358-63 *these authors contributed equally to the work
  16. Strobel A, Debener S, Anacker K, Müller J, Lesch KP, Brocke B (2004) DRD4 exon III genotype influence on the auditory evoked novelty P3. Neuroreport 15:2411-2415
  17. Murphy DL, Lerner A, Rudnick G, Lesch KP (2004) Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Mol Interv 4:109-123
  18. Di Pino G, Mössner R, Lesch KP, Lauder JM, Persico AM (2003) Serotonin roles in neurodevelopment: more than just neural transmission. Curr Neuropharmacol 2:403-417
  19. Lesch KP, Gutknecht L (2004) Pharmacogenetics of the serotonin transporter. Prog Neuropsychopharmacol Biol Psychiatry (im Druck)
  20. Lesch KP (2004) Gene - environment interaction and the genetics of depression. J Psychiatry Neurosci 29:174-84
  21. Schmitt A, Lesch KP (2004) Serotonin transporter and treatment response: an update. Pharmacogenetics (im Druck)
  22. Lesch KP, Heils A (2004) Malignes Neuroleptisches Syndrom vs. Akute lebensbedrohliche Katatonie. In: Jahn T (Ed) Bewegungsstörungen bei psychischen Erkrankungen. Springer, Berlin, pp 61-73
  23. Lesch KP (2004) The genetics of depression in the postgenomic era. In: den Boer JA, ter Horst GJ, George M (Eds.) Current and future developments in psychopharmacology. Benecke, Amsterdam, pp 159-173
  24. Lesch KP (2004) Genetics of Anxiety and Related Disorders: Implications for Pharmacogenetics. In Gorwood P, Hamon M. Psychopharmacogenetics. Kluwer Academic/Plenum, New York (im Druck)