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Publikationen 2002

Publications 2002

  1. Schmitt A, Asan E, Lesch KP, Kugler P (2002) Cloning and expression of a glutamate transporter GLT1 variant form rat brain. Neurosci 109:45-61

  2. Bennett AJ, Lesch KP, Heils A, Long J, Lorenz J, Shoaf SE, Champoux M, Suomi SJ, Linnoila M, Higley JD (2002) Early experience and serotonin transporter gene variation interact to influence primate CNS function. Mol Psychiatry 7:118-122

  3. Meyer J, Ortega G, Nürnberg G, Saar K, Rüschendorf F, Wienker T, Reis A, Stöber G, Lesch KP (2002) Exclusion of the neuronal nicotinic acetylcholine receptor a7 subunit gene as a candidate for catatonic schizophrenia in a large family supporting the chromosome 15q13-22 locus. Mol Psychiatry 7:220-223

  4. Devaney JM, Donarum E, Brown KM, Meyer J, Lesch KP, Stephan DA, Pulver AE (2002) Missense mutation of WKL1 is not etiologic of schizophrenia in a focused pedigree set. Mol Psychiatry (in press)

  5. Sand P, Schlurmann K, Luckhaus C, Götz M, G. Stöber G, Lesch KP, Riederer P, Franke P, Maier W, Nöthen MM, Propping P, Fritze J, Deckert J (2002) Estrogen receptor 1 gene (ESR1) variants in panic disorder. Am J Med Genet 114:426-428

  6. Upton AL, Ravary A, Salichon N, Mössner R, Lesch KP, Hen R, Seif I, Gaspar P (2002) Lack of the 5-HT1B receptor and the 5-HT transporter have different effects on the segregation of retinal axons in the lateral geniculate nucleus compared to the superior colliculus. Neurosci (in press)

  7. Meyer J, Saam W, Mössner R, Cangir Ö, Ortega GR, Tatschner T, Riederer P, Wienker T, Lesch KP (2002) Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females. J Neural Transm 109: 939-946

  8. Zhou FC, Lesch KP, Murphy DL (2002) Serotonin uptake into dopamine neurons via dopamine transporters: a compensatory alternative. Brain Research 942 (2002) 109–119

  9. Samochowiec J, Kucharska-Mazur J, Horodnicki J, Lesch KP, Rommelspacher H, Schmidt LG (2002) PAX-6 gene promoter polymorphism and other factors involved in brain atrophy in alcohol dependent patients. Psychiatr Pol 36:303-310

  10. Mössner R, Dringen R, Persico AM, Janetzky B, Okladnova O, Albert D, Götz M, Benninghoff J, Schmitt A, Gerlach M, Riederer P, Lesch KP (2002) Increased hippocampal DNA oxidation in serotonin transporter deficient mice. J Neural Transm (2002) 109: 557–565

  11. Strobel A, Lesch KP, Hohenberger K, Jatzke S, Gutzeit HO, Anacker K, Brocke B (2002) No association between plymorphisms of the dopamine D4 receptor gene and novelty seeking. Mol Psychiatry (in press)

  12. Müller DJ, Schulze TG, Macciardi F, Ohlraun S, Gross MM, Scherk H, Neidt H, Syagailo YV, Grässle M, Nöthen MM, Maier W, Lesch KP, Rietschel M (2002) Mocobemide response in depressed patients: association study with a functional polymorphism in the monoamine oxidase A promoter. Pharamacopsychiatry 35:157-158

  13. Syagailoa YV, Okladnova O, Reimer E, Gräßle M, Mössner R, Gattenlöhner S, Marx A, Meyer J, Lesch KP (2002) Structural and functional characterization of the human PAX7 50-flanking regulatory region. Gene 294 (2002) 259–268

  14. Sand PG, Mori T, Godau C, Stöber G, Flachenecker P, Franke P, Nöthen MM, Fritze J, Maier W, Lesch KP, Riederer P, Beckmann H, Deckert J (2002) Norepinephrine transporter gene (NET) variants in panic disorder. Neurosci Lett 333:41-44

  15. Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, Murphy DL, Uhl GR (2002) Cocaine mechanisms: Enhanced cocaine, fluoxetine and nisoxetine place preference following monoamine transporter deletions. Neuroscience 115:153-161

  16. Meyer J, Mai M, Ortega G, Mössner R, Lesch KP (2002) Mutational analysis of the connexin 36 gene (CX36) and exclusion of the coding sequence as a candidate region for catatonic schizophrenia in a large family. Schizophrenia Res 58:87– 91

  17. Peng W, Premkumar A, Mössner R, Fukuda M, Lesch KP, Simantov R (2002) Synaptotagmin I and IV are differentially regulated in the brain by the recreational drug 3,4-methylenedioxymethamphetamine (MDMA). Mol Brain Res 108:94-101

  18. Champoux M, Bennett AJ, Shannon C, Higley JD, Lesch KP, Suomi SJ (2002) Serotonin tranporter gene polymorphism, differential early rearing, and beavior in rhesus monkey neonates. Mol Psychiatry (in press)
  19. Schmitt A, Mössner R, Gossmann IG, Fischer V, Gorboulev V, Murphy DL, Koepsell H, Lesch KP (2002) An anorganic cation transporter capable of transporting serotonin is upregulated in serotonin transporter-deficient mice. J Neurosci Res 71:701-709

  20. Meyer J, Scherer SJ, Mössner R, Lesch KP (2002) Reply concerning KIAA0027 (WKL1, MLC1) and psychosis: white matters. Mol Psychiatry 7:1037-1038
  21. Benninghoff J, Schmitt A, Mössner R, Lesch KP (2002) When cells become depressed: the impact of cell biology on novel treatment strategies for depression. J Neural Transm (in press)

  22. Lesch KP, Schmitt A (2002) Antidepressants and gene expression profiling: how to SNARE novel drug targets. Pharmacogenomics J 2:346–348
  23. Lesch KP, Greenberg BD, Bennett A, Higley JD, Murphy DL, (2002) Serotonin tranporter, personality, and behavior: toward dissection of gene-gene and gene-environment interaction. In: Benjamin J, Ebstein R, Belmaker RH (Eds.) Molecular Genetics and the Human Personality. American Psychiatric Press, Washington, D.C. pp 109-135

  24. Lesch KP (2002) Wirkmechanismus antidepressiver Behandlung: Genexpression und synaptische Plastizität, In: Riederer P, Pöldinger, Laux G (Eds.), Springer, Wien (in press)

  25. Lesch KP, Benninghoff J, Schmitt A (2002) The psychopharmacogenetic-neurodevelopmental interface: focus on serotonergic gene pathways. In: Lerer B (ed.) Pharmacogenetics of Psychotropic Drugs. Cambridge University Press, Cambridge, pp 95-126

  26. Reif A, Lesch KP (2002) Neurogenetics of personality disorders. In: D’haenen H, den Boer JA, Willner P (Eds.) Biological Psychiatry. Wiley & Sons, London, pp 1387-1412

  27. Lesch KP (2002) Neuroticism and serotonin: a developmental genetic perspective. In: Plomin R, DeFries J, Craig I, McGuffin P (Eds.) Behavioral Genetics in the Postgenomic Era. American Psychiatric Press, Washington, D.C., pp 389-423

  28. Lesch KP (2002) Gene-environment interaction in generalized anxiety disorder. In: Nutt D, Rickels K, Stein D (Eds.) Generalized Anxiety Disorders: Symptomatology, Pathogenesis and Management. Dunitz, London pp. 71-87