Publikationen 2001

Publications 2001

  1. Salichon N, Gaspar P, Upton AL, Hamon M, De Maeyer E, Picaud S, Murphy DL, Mössner R, Lesch KP, Hen R, Seif I (2001) Excessive activation of 5-HT1B receptors disrupts the formation of sensory maps in monoamine oxidase A and 5-HT transporter knock-out mice. J Neurosci 21:884-896
  2. Pan Y, Gembom E, Lesch KP, Mössner R, Simantov R (2001) Plasticity in serotonin uptake in primary neuronal cultures of serotonin transporter knockout mice. Brain Res Dev Brain Res 126:125-129
  3. Gobbi G, Lesch KP, Murphy DL, Blier P (2001) Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study. J Pharmacol Exp Ther 296:987-995
  4. Mössner R, Daniel S, Albert D, Lesch KP (2001) Modulation of serotonin transporter function by interleukin-4. Life Sci 68:873-80
  5. Meyer J, Huberth A, Ortega G, Syagailo YV, Jatzke S, Strom TM, Mössner R, Ulzheimer-Teuber I, Schmitt A, Stöber G, Lesch KP (2001) A missense mutation in a novel gene encoding a putative cation channel is associated with catatonic schizophrenia in a large pedigree. Mol Psychiatry 6:304-308
  6. La Cour CM, Boni C, Hanoun N, Lesch KP, Hamon M, Lanfumey L (2001) Functional consequences of 5-HT transporter gene disruption on 5-HT1A receptor-mediated regulation of dorsal raphe and hippocampal cell activity. J Neurosci 21:2178-2185.
  7. Mössner R, Henneberg A, Schmitt A, Syagailo YV, Grässle M, Hennig T, Simantov R, Gerlach P, Riederer P, Lesch KP (2001) Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease. Mol Psychiatry 6:350-352
  8. Syagailo YV, Stöber G, Grässle M, Reimer E, Jungkunz G, Okladnova O, Meyer J, Lesch KP (2001) Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders. Am J Med Genetics 105:168-171
  9. Sora I, Hall FS, Andrews A, Liu QR, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR (2001) Molecular mechanism of cocaine action: Combined dopamine and serotonin transporter knockouts eliminate cocaine reward. Proc Natl Acad Sci USA 98:300-305
  10. Ravary A, Muzerelle A, Darmon M, Murphy DL, Mössner R, Lesch KP, Gaspar P (2001) Abnormal trafficking and subcellular localization of an N-terminally truncated serotonin transporter protein. Eur J Neurosci 13:1349-1362
  11. Persico AM, Mengual E, Mössner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J, Gimenez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR, Murphy DL, Lesch KP, Keller F (2001) Barrel pattern formation requires serotonin uptake by thalamocortical endings, and not vesicular monoamine release. J Neurosci 21:6862-6873
  12. Lesch KP (2001) Serotonergic gene expression and depression: implications for developing novel antidepressant treatments. J Affect Disord 62:57-76
  13. Becker G, Berg D, Lesch KP, Becker T (2001) Basal limbic system alteration in major depression: a hypothesis supported by transcranial sonography and MRI findings. Int J Neuropsychopharmacol 4:21-31
  14. Lesch KP (2001) Molecular foundation of anxiety disorders. J Neural Transm 108:717-746
  15. Riederer P, Reichmann H, Janetzky B, Sian J, Lesch KP, Lange KW, Nagatsu T, Gerlach M (2001) Neural degeneratioon in Parkinson´s disease. Adv Neurol 86:125-36
  16. Murphy DL, Wichems C, Andrews A, Li Q, Uhl G, Lesch KP (2001) Genetic perspectives on the serotonin transporter. Brain Res Bull 56:487-494
  17. Lesch KP (2001) Mouse anxiety: the power of knockout. Pharmacogenet J 1:187-192
  18. Lesch KP (2001) Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs. Eur J Neuropsychopharmacol 11:457-474
  19. Lesch KP (2001) Weird world inside the brain. Lancet 358 Suppl:59
  20. Lesch KP (2001) Serotonin transporter: from genomics and knockouts to behavioral traits and psychiatric disorders. In: Briley M, Sulser F (Eds.) Molecular Genetics of Mental Disorders. Martin Dunitz Publishers, London, pp 221-267