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Publikationen 2000

Publications 2000


  1. Mössner R, Albert D, Heils A, Okladnova O, Schimpl A, Lesch KP (2000) Serotonin transporter function is modulated by brain-derived neurotrophic factor (BDNF) but not nerve growth factor (NGF). Neurochem Int 36:197-202
  2. Greenberg BD, Li Q, Lucas FR, Hu S, Sirota LA, Benjamin J, Lesch KP, Hamer D, Murphy DL (2000) Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. Am J Med Genetics 96:202-216
  3. Arranz MJ, Munro J, Birkett J, Bolonna A, Mancama D, Sodhi M, Lesch KP, Meyer JFW, Sham P, Collier DA, Murray RM, Kerwin RW (2000) Pharmacogenetics of clozapine response. Lancet 355:1615-1616
  4. Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, Lesch KP, Murphy DL, Lanfumey L, Hamon M, Martres MP (2000) Altered expression and functions of the serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. Eur J Neurosci 12:2299-2310
  5. Schmidt LG, Sander T, Kuhn S, Smolka M, Rommelspacher H, Samochowiec J, Lesch KP (2000) Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics. J Neural Transm 107:681-689
  6. Eddahibi S, Hanoun N, Lanfumey L, Lesch KP, Raffestin B, Hamon M, Adnot S (2000) Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J Clin Invest 105:1555-1562
  7. Stöber G, Meyer J, Nanda I, Wienker TF, Saar K, Knapp M, Jatzke S, Schmid M, Lesch KP, Beckmann H (2000) Linkage and family-based association study of schizophrenia and the synapsin III locus which maps to chromosome 22q13. Am J Med Genetics 96:392-397
  8. Bringmann G, Brückner R, Mössner R, Feineis D, Heils A, Lesch KP (2000) Effect of 1-trichloromethyl-1,2,3,4-tetrahydro-b-carboline (TaClo) on human serotonergic cells. Neurochem Res 25:837-843
  9. Stöber G, Meyer J, Nanda I, Wienker TF, Saar K, Jatzke S, Schmid M, Lesch KP, Beckmann H (2000) hKCNN3 which maps to chromosome 1q21 is not the causative gene in periodic catatonia, a familial subtype of schizophrenia. Eur Arch Psychiat Clin Neurosci 250:163-168
  10. Lesch KP, Heils A (2000) Serotonergic gene transcriptional control regions: targets for antidepressant drug development? Int J Neuropsychopharmacol 3:67-79
  11. Lesch KP (2000) Serotonergic gene expression and depression: implications for developing novel antidepressants. Journal of Affective Disorders 1 (2000) 000–000
  12. Li Q, Wichems C, Heils A, Lesch KP, Murphy DL (2000) Reduction in density, but not G protein coupling, of 5-HT1A receptors in 5-HT transporter mutation mice: gender and brain differences. J Neurosci 20:7888-7895
  13. Mössner R, Albert D, Persico AM, Henning T, Bengel D, Holtmann B, Schmidt A, Keller F, Simantov R, Murphy DL, Seif I, Deckert J, Lesch KP (2000) Differential regulation of adenosine A1 and A2A receptors in serotonin transporter and monoamine oxidase-deficient mice. Eur J Neurospsychopharm 10:489-493
  14. Stöber G, Saar K, Rüschendorf F, Meyer J, Nürnberg G, Franzek E, Reis A, Lesch KP, Wienker TF, Beckmann H (2000) Splitting schizophrenia: periodic catatonia is an autosomal dominant disorder with a gene on chromosome 15q15. Am J Hum Genetics 67:1201-1207
  15. Schulze TG, Müller DJ, Krauss H, Scherk H, Ohlraun S, Syagailo YV, Windemuth C, Neidt H, Grässle M, Papassotiropoulos A, Heun R, Nöthen MM, Maier W, Lesch KP, Rietschel M (2000) Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder. Am J Med Genetics 96:801-803
  16. Deckert J, Meyer J, Catalano M, Sand P, Di Bella D, Ortega G, Stöber G, Franke P, Nöthen MM, Fritze J, Maier W, Beckmann H, Propping P, Bellodi L, Lesch KP (2000) Novel 5'-regulatory region polymorphisms of the 5-HT2C receptor gene: association study with panic disorder. Int J Neuropsychopharmacol 3:321-325
  17. Sand P, Godau C, Riederer P, Peters C, Franke P, Nöthen MM, Stöber G, Fritze J, Maier W, Propping P, Lesch KP, Riess O, Sander T, Beckmann H, Deckert J (2000) Exonic variants of the GABAB receptor gene and panic disorder. Psychiat Genetics 10:191-194
  18. Lesch KP, Merschdorf U (2000) Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behav Sci Law 18:581-604
  19. Mössner R, Schmitt A, Syagailo YV, Gerlach P, Riederer P, Lesch KP (2000) The serotonin transporter in Alzheimer's and Parkinson's disease. J Neural Transm Suppl 60:345-350